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Avoid excessive exposure to wind or coldExtremes of climate tend to dry or burn normal skinSkin treated with RETIN-A may be more vulnerable to these extremesYour physician can recommend ways to manage your acne treatment under such conditions.

RETIN-A is indicated for topical application in the treatment of acne vulgarisThe safety and efficacy of the long-term use of this product in the treatment of other disorders have not been established.

Once the acne lesions have responded satisfactorilyit may be possible to maintain the improvement with less frequent applicationsor other dosage forms.

Do not use skin products that contain benzoyl peroxidesulfurresorcinolor salicylic acid unless otherwise directed by your doctorThese products can cause severe skin irritation if used with tretinoin topical.

Skin drynessburningrednessexcessive flaking or peelingIf you develop these symptoms your healthcare provider may tell you to stop using it for a whiledecrease the number of applicationsor stop using it completely.

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there is some evidence that long-term, high-dose, or multiple courses of therapy with isotretinoin have more of an effect than a single course of therapy on the musculoskeletal system.

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